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IntusCare Announces PACE Organization of Rhode Island is First to Deploy Innovative EMR and Practice Management System Platform

Intus Care

IntusCare, a technology leader in the PACE market, today announced that PACE Organization of Rhode Island (PACE-RI) has officially gone live with IntusCare CareHub, an EMR and practice management system built for PACE’s value-based care model. PACE-RI is one of the nation’s most innovative Programs of All-Inclusive Care for the Elderly (PACE). The successful launch marks a major milestone in a years-long partnership between the two organizations that has been defined by co-creation, trust, and an implementation model centered on deep collaboration. To prepare PACE-RI for the launch, IntusCare delivered a fully immersive, white-glove implementation for PACE-RI, reflecting its commitment to long-term success. The support included in-person workflow discovery sessions with operational subject matter experts and super users, as well as twice-weekly SOP alignment meetings to evolve internal processes alongside CareHub’s capabilities. IntusCare also led a four-day, on-site training bootcamp spanning multiple PACE-RI centers and conducted weekly readiness scoring calls with PACE-RI leadership. During go-live, the team implemented a three-day, center-wide support structure and ensured hands-on involvement from IntusCare’s product team throughout every stage of the process. “This wasn’t just a rollout, it was a joint effort to reimagine how our teams work and collaborate,” said Joan Kwiatkowski, MSW, Chief Executive Officer at PACE-RI. “What excites us most about CareHub is that it’s built for PACE, with PACE. From the start, it’s been thoughtfully designed around the unique needs of our model. We’re confident it will help us operate more efficiently and stay better connected across teams.” In the months ahead, CareHub is expected to deliver measurable gains in interdisciplinary team coordination, reduce documentation time, and improve visibility across clinical and operational workflows. “The ability to link CareHub with other IntusCare products like IRIS and Analytics creates a powerful, all-in-one solution for our clinical and administrative teams,” said Liz Boucher, Chief of Organizational Performance at PACE-RI. CareHub will help us work more efficiently and reduce the burden on staff, creating a happier workforce and freeing up time to focus on caring for our participants. And when we can spend more time with participants, we see better outcomes—especially when paired with easier access to key data that enables earlier, more effective interventions.” PACE-RI’s leadership and frontline staff have played a foundational role in the development of CareHub through their work on the CareHub Product Steering Committee, whose input has directly shaped features like IDT tasking tools, intuitive care planning modules, and embedded compliance support. That collaboration will continue as PACE-RI expands its use of CareHub and helps guide future enhancements. “As our first partner, PACE-RI has helped us build something truly transformative for the PACE community,” said Robbie Felton, Chief Executive Officer at IntusCare. “This go-live isn’t just the culmination of a product build—it’s the start of a new era in how technology supports participant care.” About IntusCare ‍IntusCare is the only end-to-end ecosystem built specifically to help PACE programs deliver exceptional care, strengthen financial performance, and stay compliant. IntusCare replaces outdated technology and manual workaround with purpose-built tools for care coordination, risk adjustment, population health, and utilization management. IntusCare empowers teams to take control of their operations and improve outcomes for dual-eligible seniors – some of the most socially vulnerable and clinically complex individuals in the U.S. healthcare system. Visit our website to learn more intuscare.com. About PACE-RI PACE-RI is the non-profit health plan for adults 55 and older who are nursing home eligible but wish to remain living at home. PACE-RI provides both insurance and medical care, as well as a range of health and social services that include adult day care, transportation, and meals. Taking a comprehensive approach to well-being, PACE-RI is able to keep its medically complex participants in the community for an extra four years on average. With center locations in East Providence, Newport, Westerly, and Woonsocket, PACE-RI’s 200 employees serve the entire state. The Program of All-inclusive Care for Elders is a federally designated model overseen by CMS that is now in 33 states serving 80,000 participants. Learn more: PACE Organization of Rhode Island | Services for the Elderly Contact Details SVM Public Relations +1 401-490-9700 intuscare@svmpr.com Company Website https://www.intuscare.com/

May 14, 2025 10:00 AM Eastern Daylight Time

Annual Giant Sequoia Lands Coalition Progress Report Highlights Significant Advances in Emergency Wildfire Recovery, Research and Restoration

Save the Redwoods League

Officials from the State of California, USDA Forest Service, National Park Service, Tule River Indian Tribe of California, Save the Redwoods League and other members of the Giant Sequoia Lands Coalition (GSLC) today announced significant progress in their work to protect the largest trees on Earth from extreme wildfires. In its 2024 progress report, the GSLC confirms coalition partners have conducted restoration activities in more than half of the world’s sequoia groves since 2022, reducing the risk of extreme wildfires and improving overall forest health. “The Giant Sequoia Lands Coalition has made remarkable progress in defending the largest trees in the world from the growing threat of extreme megafires,” said coalition Co-Chair Kevin Conway, state forests program manager for CAL FIRE. “With meticulous research we’re gaining critical insight into the changing dynamics of these fire-adapted ecosystems. Through strategic fuel reduction and other restoration efforts across thousands of acres we’re actively making forests healthier. What began as a shared commitment in the face of crisis has evolved into a deeply rooted collaboration, built on trust, expertise and a commitment to the survival of giant sequoias.” Giant sequoia ecosystems provide essential habitat for wildlife, store vast amounts of carbon, protect headwaters and water quality, support the cultural and spiritual practices of Tribal Nations and anchor a thriving outdoor recreation economy. In the past decade, approximately 20% of the world’s mature giant sequoias died from megafires, primarily during the catastrophic fires of 2020 and 2021. Years of fire exclusion, drought and increasing temperatures were the primary drivers of the severe wildfires that killed these magnificent trees. The GSLC formed in 2022 in the face of this existential crisis. 2024 Highlights from the Report: Scientific Advancements: Leading giant sequoia ecologists published new research on post-fire regeneration and the emerging threats of native bark beetles. The GSLC also launched monitoring efforts to understand the health and vulnerabilities of giant sequoias. Ongoing research and monitoring provide a scientific basis for restoration programs and inform best practices across the sequoia range. Two recent publications discuss the substantial risk of losing portions of giant sequoia groves due to high tree mortality rates and inadequate natural recovery if no intervention is taken. Innovation: In May a health inspection of the world’s largest tree, General Sherman, was organized by GSLC members and led by the National Park Service and Ancient Forest Society. Three different technologies were used in the study, and the tree was found to be in good health. Cultural Burning Returns: Members from the Tule River Indian, North Fork Mono, and Tübatulabal Tribes led two cultural burn demonstrations within a giant sequoia grove, sharing their deep knowledge and raising awareness for this important land stewardship practice. The cultural burns were held at the Alder Creek Grove in collaboration with Save the Redwoods League and other coalition members. Rapid Wildfire Response: During the Coffee Pot Fire in Tulare County in August 2024, the GSLC members mobilized swiftly to protect vulnerable groves in Sequoia National Park and neighboring lands managed by the Bureau of Land Management. Approximately 12 large sequoias were killed by the wildfire, but overall large tree losses were kept to a minimum because of the swift actions of firefighters and the GSLC. The GSLC’s restoration work in 2024 was managed by 1,652 personnel. Since 2022, the GSLC has completed 18,743 acres of restoration treatments in 44 giant sequoia groves, and 8,500 acres of treatments in forests surrounding the groves. Fire exclusion, combined with drought and rising temperatures, has resulted in a hazardous and unnatural buildup of combustible plant materials (fuels) within and surrounding the groves. Restoration work increases the wildfire resilience of the groves by reducing the amount of fuels through manual and mechanical reductions, prescribed fires and cultural burning practices. Without these efforts, the groves are susceptible to wildfires that burn with an intensity that far exceeds the historical fires that giant sequoias evolved with, fires that they need to reproduce and regenerate. More than 74,800 native trees were planted in 2024 within groves to aid in forest recovery, raising the total to more than 617,000 native trees in the last three years. Reforestation projects focus on areas that experienced uncharacteristically high wildfire intensity where seed trees have died, burned seeds were not able to develop and minimal regeneration was naturally occurring. The full report is available here. “The Giant Sequoia Lands Coalition originated in a time of crisis. Today, it is a model for collaboration, restoration, and stewardship based in science and ecocultural knowledge,” said Ben Blom, director of stewardship and restoration for Save the Redwoods League and chair of the GSLC restoration working group. “We are poised to deepen our impact across the range in 2025. We’ve accomplished a lot as a coalition, but the work is far from done. We need to keep our momentum going to protect these irreplaceable American forests at the scale they need to thrive.” “Despite significant progress, the restoration work is far from done. The threats to giant sequoias remain urgent, and restoration at the scale required demands long-term coordination, sustained funding and supportive policies,” continued Blom. The members of the Giant Sequoia Lands Coalition include: California Department of Forestry and Fire Protection (CAL FIRE), stewards of Mountain Home Demonstration State Forest California State Parks, stewards of Calaveras Big Trees State Park National Park Service, represented by Sequoia and Kings Canyon National Parks and Yosemite National Park Tulare County, stewards of Balch Park Tule River Indian Tribe of California, stewards of all or parts of five sequoia groves University of California, Berkeley, stewards of Whitaker’s Forest USDA Forest Service, represented by the Sequoia National Forest, Giant Sequoia National Monument, Sierra National Forest, and Tahoe National Forest U.S. Department of Interior, Bureau of Land Management, stewards of Case Mountain Extensive Recreation Management Area GSLC Affiliate Members: American Forests, Ancient Forest Society, Giant Sequoia National Monument Association, Save the Redwoods League (stewards of a section of the Alder Creek Grove), Sequoia Parks Conservancy, Southern Sierra Conservancy, Stanislaus National Forest, US Geological Survey—Western Ecological Research Center and Yosemite Conservancy. Note to media: Images of GSLC projects and places are available for download here. * * * About Giant Sequoia Lands Coalition The Giant Sequoia Lands Coalition (GSLC) is a landscape-scale, multi-partner collaboration dedicated to the conservation and stewardship of giant sequoia grove ecosystems. Our coalition is composed of all federal, tribal, state and local agencies and organizations that manage giant sequoia groves in public, tribal or private nonprofit ownership. Our affiliate partners include select federal and state conservation agencies, nongovernmental organization conservation groups, and academic research partners with a shared commitment to protect and steward giant sequoias and their ecosystems from emerging threats associated with climate change and the extended absence of natural, low-severity wildfire processes on the landscape. Learn more at giantsequoias.org. # # # Contact Details Landis Communications Inc. Robin Carr +1 415-766-0927 redwoods@landispr.com Company Website https://giantsequoias.org

May 13, 2025 07:55 AM Pacific Daylight Time

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UNFTR Launches ‘5 Non-Negotiables’ Campaign to Advance Bold Progressive Agenda

UNFTR

UNFTR ( UNFTR.com ), known for its incisive analysis of American politics and unwavering commitment to progressive values, today announced the launch of its “5 Non-Negotiables” campaign. This new action aims to galvanize support for a transformative progressive agenda, directly confronting what the podcast views as the Democratic establishment’s fundamental inability to deliver meaningful change. The 5 Non-Negotiables—Housing First, Civilian Labor Corps, Medicare for All, Election Integrity, and Climate Action—represent a progressive alternative to the compromised politics that have dominated the corporate-bought duopoly for decades. “The Democratic establishment has consistently been dismissive of progressive priorities in the name of pragmatism and moderation,” said Max, host of UNFTR. “And to what end? Americans are confronting a housing crisis, shareholder-run healthcare system, corporate capture of elections and legislative processes, and a largely forgotten climate emergency, among other critical issues. The 5 Non-Negotiables reject that approach entirely. This isn’t about moving the Overton window slightly—it’s about a bold progressive vision that refuses to compromise on the fundamentals of what makes a just society.” The campaign is the capstone of UNFTR’s podcast series exploring essential progressive priorities, now condensed into comprehensive policy proposals backed by research and historical context: Housing First: Recognizing stable shelter as a human right and economic necessity, with evidence showing 85–90% of participants remain housed after the first year and savings of $10,000–$20,000 per person annually. Civilian Labor Corps: Responding to AI disruption threatening millions of jobs and vagaries of our capitalist boom-and-bust cycles thrusting workers into precarity by creating guaranteed meaningful work focused on climate resilience, care work, and community development. Medicare for All: Transforming a healthcare system that consumes 18% of the American economy while delivering poorer outcomes than other developed nations. Election Integrity: Reclaiming democracy from special interests through constitutional reform that addresses the corrupting influence of money in politics. Climate Action: Establishing a Climate Trust that ensures those who have contributed most to the crisis help fund solutions, generating substantial resources for resilience and adaptation. “When the Democratic establishment tells progressives to moderate our demands or ‘not to let the perfect be the enemy of the good,’ they’re repeating the failed formula that has led to our current crises,” added Max. “The 5 Non-Negotiables give progressives a platform that doesn’t just react to the right, but articulates a positive vision for transforming society. Simply being anti-Trump isn’t enough, as evidenced by the Democratic Party’s incredibly poor standing with the American public.” The campaign provides progressives with practical tools for organizing at the grassroots level, independent of party structures. The website ( UNFTR.com/5nn ) includes downloadable policy briefs, social media posts, and email templates for contacting representatives. UNFTR’s goal is to empower Americans exhausted of being pushed aside as the wealthy gain disproportionately more power. For more information about the 5 Non-Negotiables campaign, visit UNFTR.com/5nn. To interview Max, email max@unftr.com. Founded in 2020, UNFTR is a progressive political podcast and media platform dedicated to providing in-depth, well-researched analysis of political, social, and economic issues affecting Americans. UNFTR produces a weekly podcast The New York Times called “consistently compelling and educational,” twice-weekly newsletter, and related video essays. Learn more at UNFTR.com. Contact Details UNFTR Media, LLC max@unftr.com Company Website https://www.unftr.com/

May 13, 2025 09:00 AM Eastern Daylight Time

Players Health and MaxU Partner to Power the Next Generation of Mentally Resilient Athletes

Players Health

In a bold move to redefine athlete development, Players Health and MaxU today announced a strategic partnership to bring elite-level mental skills training to youth athletes across North America. Unveiled during Mental Health Awareness Month, this strategic alliance is both timely and purpose-driven. As mental health emerges as a cornerstone of athletic excellence and personal growth, Players Health and MaxU unite around a shared mission: to empower the whole athlete with transformative mindset tools that go beyond the game. Both organizations are anchored in a bold belief—mental health and performance are vital to athlete safety, now and into the future. This partnership integrates MaxU’s groundbreaking mental performance platform directly into the Players Health ecosystem—empowering young athletes with the focus, confidence, and resilience needed to thrive in sports, school, and life. “This is more than a partnership—it’s a movement,” said Dan Greco, Co-Founder of MaxU. “Together, we’re scaling access to proven mental skills training that helps athletes navigate pressure, unlock peak performance, and build habits that last a lifetime.” With a reach spanning teams, schools, and youth organizations, the impact is immediate and scalable—creating a new blueprint for how mental wellness and performance are taught, measured, and mastered in youth sports. “Over the last several years since joining Players Health, I've been focused on creating an environment where every young athlete feels supported in every part of their journey,” said Kyle Lubrano, Chief Athlete Safety Officer of Players Health. “Mental resilience is the foundation for everything else — confidence, physical performance, and long-term success. Partnering with MaxU allows us to deliver real, lasting change for athletes and families everywhere. This allows us to provide kids with the tools to believe in themselves, thrive under pressure, and carry those skills through every stage of life.” Two missions. One movement. Grounded in purpose and fueled by innovation, this alliance between Players Health and MaxU reflects a shared belief: supporting the whole athlete—physically, mentally, and emotionally—is not just the future of youth sports. It’s the standard. Players Health is a sports technology company providing digital risk management services, reporting tools and insurance products to sports organizations to empower them to stay ahead of their ever-changing safety and compliance responsibilities. Working towards establishing the safest environment for athletes, Players Health views the health and safety of athletes as a priority in today's sports landscape. Contact Details Jackson Gaskins playershealth@hotpaperlantern.com MaxU Contact MaxU info@maxu.co Company Website https://www.playershealth.com

May 13, 2025 09:00 AM Eastern Daylight Time

Roberts & Ryan Inc. Welcomes Rear Admiral Matthew Ott (Ret.) to its Advisory Board

Roberts & Ryan, Inc.

Roberts & Ryan Inc., America’s first Service-Disabled Veteran-Owned Broker Dealer, is pleased to announce that Rear Admiral Matthew Ott (Ret.) has joined the firm’s Advisory Board. Mr. Ott is the founder and CEO of Ott and Associates and the firm On Target Together. He is a retired U.S. Navy Rear Admiral, where he served on amphibious assault ships, destroyers, and aircraft carriers and served across all levels of tactical, operational, and strategic warfare. Accomplished in command overseas and in the U.S., his service ranged from Secretary of Defense Staff, Defense Logistics Agency, U.S. Fleet Forces Command, Naval Supply Systems Command, and culminated in his third return to NAVSUP Weapon Systems Support, leading 2,500 team members across three sites, providing global supply chain management functions for 3,900+ aircraft and 300 ships, submarines, and nuclear reactors for the Navy, Marine Corps, and 80 global partners. A decorated 32-year career officer, Ott is a recognized authority on Supply Chain Management, Complex Systems Architecture, bridging Industry and Government, executing Humanitarian and Disaster Response, and creating tough, winning teams. Ott is best known for enhancing the Navy Sustainment System Supply Architecture as its key material director in the 41B strategic scale design of Navy-wide supply chains to run more effectively and affordably. The complex launches covered aviation, maritime, shipyard, maintenance repair and overhaul, nuclear, ordnance and subsistence markets. A Human Centered Design expert, he creates value using real-time visualization and horizontally integrates complex systems. His leadership, coaching, process discipline and refinement allow stakeholders to win in high stakes environments. His teams are creative, action-oriented, accountable, and focused on leveraging untapped potential to unlock value. Ott received a B.A. in Economics and Business from the Virginia Military Institute. He holds an MBA from the University of North Carolina at Chapel Hill with concentrations in Supply Chain Management and E-business and Digital Commerce. He is a distinguished graduate of the National Defense University’s Industrial College of the Armed Forces (ICAF), where he earned an M.S. in National Security and Resource Strategy. Ott is also Vice President, Partnerships and Alliances for Throughline, an Enterprise Strategy and Design firm where he will continue to bring his military ethos to the commercial world. He speaks about lessons learned, applicability of cross-functional approaches, and applies frameworks to complex problems in the defense, commercial, start-up, small business, and NGO spaces. He is available to serve C-Suite advisory level and teams to be On Target Together. For more on his U.S. Navy Background, please visit the U.S. Navy Website. About Roberts and Ryan, Inc. Roberts & Ryan, Inc. is a Service-Disabled Veteran Owned (SDVO) broker-dealer with execution capabilities in the capital markets, equities, and fixed-income trading. The firm was founded in 1987 by a United States Marine Corps Vietnam combat veteran and Purple Heart recipient. With over $2.38 million in committed donations, Roberts & Ryan is active in donating to charitable foundations that make significant positive impacts in the lives of Veterans and their families, focusing primarily on general wellness, mental health, and career transition. To learn more about Roberts & Ryan, please visit www.roberts-ryan.com. Securities are offered by Roberts & Ryan Inc., member FINRA | SIPC | MSRB | NYSE | NASDAQ. Contact Details Michael C. Del Priore +1 646-859-4061 mdelpriore@roberts-ryan.com Company Website https://www.roberts-ryan.com

May 12, 2025 09:00 AM Eastern Daylight Time

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PowerPollen Receives Foundational Patent for Groundbreaking Pollen Storage Methodology

PowerPollen

PowerPollen, an agtech company improving crop pollination for increased agricultural productivity and profitability, has received U.S. Patent 12,245,587 for its groundbreaking process of using solid particulates blended with fresh pollen grains to protect pollen’s viability during storage. As the industry leader in commercial scale pollen collection, application and storage, PowerPollen’s IP strategy has been a key part of protecting their innovation while rapidly scaling to support global seed companies and farmers since the company was founded in 2015. PowerPollen collects, preserves and applies pollen to corn, wheat, rice, and other important crops, eliminating the previously required dependency on natural pollen shedding to pollinate female plants. This process enables the ability to more reliably and cost-effectively produce high-quality seed farmers plant for crops. Corn, rice, wheat and barley rank as the top four grain crops grown globally. This patent is part of a one-of-a-kind portfolio of intellectual property PowerPollen has secured in their pursuit to increase the productivity, profitability and sustainability of modern agricultural practices. “Our initial key discoveries more than a decade ago – and our ongoing innovation since – has enabled PowerPollen to scale our unique pollination tech stack of collection, storage and application to commercial levels in agriculture—helping farmers and seed production partners increase yields without increasing other inputs,” said Jason Cope, Chief Intellectual Property Officer, PowerPollen. “Our discoveries changed the previously held notion that row crop pollen was not capable of being stored for any duration. The ripple effect can clearly be seen by the consistent yield improvements in fields that PowerPollen has treated with stored pollen.” Achieving Production and Sustainability in Modern Agricultural Practices In 2015, PowerPollen began looking for ways to improve in-field crop pollination by collecting pollen and storing it for targeted application. In their discovery process, the greatest problem they encountered was that pollen tends to form large clumps when stored, which results in a rapid decline in pollen health. “We theorized that when a pollen grain dies, its walls lose integrity and the contents of the dead cell leak out, contacting other pollen grains in the batch being stored,” Cope said. “This causes adjacent pollen grains to die, resulting in the large clumps of dead pollen cells.” PowerPollen created a unique, cost-effective production process that blends fresh pollen with different materials that separate the live pollen grains from each other. This now patented process prevents the live pollen grains from contacting any material leaked from dead pollen grains, thus dramatically extending and prolonging the pollen’s viability. Today, PowerPollen holds the most patents for pollination-based technology, crop application and related innovations, based on over a decade of intellectual data and discovery and more than eight years of commercial field data and ongoing innovation. Because of its novel technology and the founders’ understanding of marketplace realities, IP strategy has been a critical part of the business to usher in the best technology advancements for customers. Patent Reinforces PowerPollen's Leadership in Pollination Technology for Agriculture “Seed crop producers today use incredibly innovative breeding techniques yet risk it all with pollination methods that haven’t changed for generations,” Cope said. “With this patent claim, we continue to execute our IP strategy focused on the foundational building blocks of pollination-enabling technologies – and advancing this innovation across crops and geographies at the pace, scale and reliability critical to advancing higher-yield and climate-resilient food production.” Seed industry partners already look to PowerPollen’s ability to practice on-demand pollination even within fields that are planted in the normal male to female row ratio. Pollination efficiency is the key rate limiting factor for yield and kernel quality. Further, producers can improve their seed purity by intentionally applying quantities of desirable pollen, which out competes undesirable pollen. By ensuring yield, quality and purity are all maximized, PowerPollen can generate significantly more value per acre. PowerPollen’s technology will be used on thousands of acres again this season across the U.S., with expansion planned globally. Customers interested in a demo or learning more can contact PowerPollen.com. PowerPollen offers a breakthrough, scalable technology to collect, preserve and apply pollen on-demand to help improve the productivity, profitability and sustainability of modern farming practices. Following multiple seasons of year-round field trials, PowerPollen’s patented pollination technology increases yield and improves the quality of commercial hybrid corn seed production. The company has applied its technology across thousands of commercial acres over the past several years. PowerPollen is headquartered in Iowa with additional research operations in Puerto Rico and Texas. Learn more about how PowerPollen’s on-demand pollination technology works at www.powerpollen.com. Contact Details AgTech PR Jennifer Goldston jennifer@agtechpr.com Company Website https://powerpollen.com

May 06, 2025 08:30 AM Central Daylight Time

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Nuvectis Pharma's NXP900: Could This Revolutionary Cancer "Inactivator" Transform Oncology Treatment?

Global Markets News

Investors seeking the next breakthrough in precision oncology may want to take note of Nuvectis Pharma (NASDAQ: NVCT)*, a clinical-stage biopharmaceutical company developing, among other candidates, NXP900 - which a a new analysis is describing not merely as a cancer inhibitor, but a complete cancer pathway "inactivator." The new analysis, published on notable investment newsletter “ Truffle Pigs ”, provided a comprehensive review of Nuvectis Pharma’s NXP900. Beyond Traditional Inhibition According to the Truffle Pigs blog, NXP900 represents something entirely new in cancer treatment. Unlike traditional kinase inhibitors that merely slow cancer signaling, NXP900 is characterized as the "first SRC kinase inactivator" - a distinction that could prove crucial in the fight against resistant cancers. The analysis highlights that NXP900 functions as a "type 1.5 inhibitor" that locks the SRC kinase in its inactive state, effectively shutting down all cancer signaling pathways and keeping them disabled between doses. This complete inactivation mechanism potentially offers a significant leap beyond current therapies. Promising Clinical Data Recent data presented at the 2025 American Association for Cancer Research (AACR) meeting appears to support this thesis. According to the analysis, NXP900 demonstrated: Perhaps most intriguing were results showing that when combined with AstraZeneca's blockbuster drug osimertinib (Tagrisso), NXP900 demonstrated significant tumor regression and extended tumor control even after treatment ended - suggesting potential for durable responses or even complete responses in certain patients. Dual Market Opportunity The analysis notes two major market opportunities for NXP900: Single-agent therapy for SRC/YES1-driven tumors, potentially addressing approximately 20,000 lung cancer patients annually Combination therapy for overcoming acquired resistance to targeted drugs like osimertinib (EGFR) or lorlatinib (ALK), potentially addressing up to 70,000 non-small cell lung cancer patients annually While established companies like AstraZeneca generate nearly $7 billion annually from Tagrisso targeting approximately 20,000 new EGFR-mutated patients each year, Truffle Pigs' analysis suggests NXP900's broader applicability could potentially drive peak sales of $12-15 billion across various cancer indications. Investor Perspective With only 23 million shares outstanding and a current market cap of 219 million, Nuvectis represents a high-risk, high-reward opportunity typical of early-stage biotech. The company recently raised capital through a public offering of common stock, extending its cash runway into 2027 on what many would consider impressive terms given the market backdrop. Phase 1b trials targeting biomarker-selected cancers are expected to commence shortly, with potential clinical response data anticipated later this year.Notably, the original blog highlighted that that while the author held a position in Nuvectis Pharma (NASDAQ: NVCT), he was not compensated to write or publish the content. In other words, one might say that the author has “skin in the game”. As with all development-stage biotechnology companies, significant risks remain. analysis appropriately notes that as with all companies in the field - regulatory approval hurdles, high clinical failure rates, capital intensity, potential market competition, uncertain revenue streams, and broader economic factors all present considerable risks that investors should take into account when conducting their due dilligence. The full Truffle Pigs Blog post is available here: https://trufflepigs.substack.com/p/nuvectis-pharmas-nxp900-the-first Recent News From Nuvectis Pharma Nuvectis Pharma Provides Poster Presentation Highlights for NXP900 from the 2025 AACR Meeting Nuvectis Pharma Announces Upcoming Presentations for NXP900 at the 2025 American Association for Cancer Research Meeting Nuvectis Pharma Announces a New Publication of a Research Study Demonstrating that the Combination of NXP900 and EGFR Inhibitors Improves the Efficacy of the EGFR Inhibitors in Preclinical Models of EGFR Mutated NSCLC Legal Disclaimer & Disclosure: Nothing in this report constitutes financial or investment advice, nor does it represent an offer to buy or sell securities. This alert is published by Wall Street Wire™, a promotional content network and platform serving issuers around the globa. The operators of Wall Street Wire are not registered brokers, dealers, or investment advisers. This distribution is paid promotional content related to Nuvectis Pharma and was produced as part of their paid subscription to Wall Street Wire. This report has not been reviewed or approved by Nuvectis Pharma prior to publication. Please review the full disclaimers and compensation disclosures here: redditwire.com/terms. Readers are advised to refer to the full original blog post mentioned in the report and the disclosures it may be subject to. Contact Details WALL STREET WIRE Editorial Desk media.globalmarkets@gmail.com

May 05, 2025 01:59 PM Eastern Daylight Time

Spring Bird Delivers Transit Buses to MTR for Use in Major Construction Shuttle Operations

Spring Bird

Spring Bird has delivered six heavy-duty New Flyer D40LF transit buses to MTR, providing dedicated shuttle support for a large-scale semiconductor fabrication plant construction site. The buses will be used to safely and efficiently transport construction workers across the expansive site, reflecting the growing demand for durable, high-capacity shuttle solutions in complex infrastructure projects. The multi-bus order, fulfilled over the past year through several transactions, underscores Spring Bird’s rising role as a trusted supplier of transit buses for industrial and operational shuttle services. According to Spring Bird founder Elliott Carson, the deal came together due to “competitive pricing, fast turnaround, and strong warranty support,” all of which aligned with MTR’s high standards and tight project timelines. “This partnership with MTR is a great example of what happens when two teams are aligned in purpose and professionalism,” said Carson. “MTR had a clear vision, high standards, and a fast-moving project — and we were proud to meet that challenge. Supporting their shuttle operations with dependable, work-ready transit buses is exactly what Spring Bird is built to do.” The buses underwent standard make-ready servicing and were delivered ready for immediate deployment. While not retrofitted with low-emission or advanced telematics systems in this case, the New Flyer D40LF platform offers reliable performance, ample standing room, and durability that outperforms most traditional coach or cutaway vehicles under demanding, repetitive shuttle conditions. “Transit buses are built for this kind of work,” said Thomas Hoskins, Director of Operations at Spring Bird. “You’re moving large numbers of people, constantly, in stop-and-go patterns, sometimes on rough or temporary roads. These vehicles are designed for all-day, every-day use. They can load quickly, handle tough environments, and just keep going.” Spring Bird’s Construction Shuttle Service program highlights several key benefits of using heavy-duty transit buses in worksite transportation: Dual-door boarding allows faster loading and unloading compared to coach buses or vans. Low-floor designs increase accessibility and reduce boarding times. Higher standing capacity allows more flexible loading based on shift schedules. Cost-efficiency comes from needing fewer buses and drivers to move more people in less time. For MTR, choosing Spring Bird also meant working with a team that understands the complexity of operational logistics. “We’re proud to support partners like MTR who are helping to build the future—literally,” said Carson. “Whether it’s a long-term city transit solution or a short-term industrial project, our goal is always the same: safe, smart, dependable transportation.” The deal also adds another chapter to the Carson family’s eight-decade history in the transit industry. Spring Bird, founded by Elliott Carson in 2020, is built on a legacy that dates back to 1943 when Dean Carson began providing local transit in Los Angeles. Today, that commitment to innovation, service, and reliability lives on in Spring Bird’s growing footprint across public and private transportation sectors. About Spring Bird Spring Bird is a premier provider of transportation solutions, specializing in the sale, leasing, and service of heavy-duty transit buses and motor coaches. Drawing from the rich Carson family legacy in the transportation industry, Spring Bird offers an inventory of high-quality buses from leading manufacturers and provides customized rehabilitation services, including minor repairs, major overhauls, and technological retrofitting. Dedicated to safety, innovation, and customer satisfaction, Spring Bird addresses the unique needs of cities, transit agencies, and private operators, ensuring reliable and efficient transportation solutions. Media Contact: For more information, visit https://springbirdbus.com or contact us at press@springbirdbus.com. ### About Spring BirdSpring Bird is a premier provider of transportation solutions specializing in the sale, leasing, and service of heavy-duty transit buses and motor coaches. Drawing from the rich Carson family legacy in the transportation industry, Spring Bird offers an inventory of high-quality buses from leading manufacturers and provides customized rehabilitation services, including minor repairs, major overhauls, and technological retrofitting. Dedicated to safety, innovation, and customer satisfaction, Spring Bird addresses the unique needs of cities, transit agencies, and private operators, ensuring reliable and efficient transportation solutions. Contact Details Media Contact press@springbirdbus.com Company Website https://springbirdbus.com

April 30, 2025 10:41 AM Central Daylight Time

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Nutriband Inc (NASDAQ: NTRB) Solution To Fentanyl Abuse Could Translate To $200 Million In Peak Revenue

NTRB

Nutriband Inc. (NASDAQ:NTRB) is a pharmaceutical company with a specific focus on developing a portfolio of transdermal pharmaceutical products. The company’s lead product under development is AVERSA™ Fentanyl, which is on track to becoming the first-ever abuse-deterrent transdermal fentanyl patch. AVERSA Fentanyl is currently pursuing a 505(b)(2) registration pathway, which should make it eligible for a more expedited review. For context, AVERSA is Nutriband’s proprietary technology that can be incorporated into any transdermal patch to prevent the abuse, misuse, diversion, and accidental exposure of drugs with the potential for abuse, like opioids. What makes AVERSA unique is its aversive agent coating, which leverages taste aversion to deter oral abuse and accidental exposure to transdermal opioid patch products. More than 70% of fentanyl patch abusers choose oral routes to abuse, so taste aversion addresses primary routes of abuse. That means AVERSA technology has the potential to improve the safety profile of transdermal drugs susceptible to abuse, such as fentanyl, while making sure that these drugs remain accessible to those patients who really need them. In one of the company’s recent major corporate milestones, Nutriband announced that it had received notification that its patent had been granted in Macao, which protects its AVERSA abuse-deterrent transdermal technology. The technology is now covered by a broad international intellectual property portfolio with patents issued in 46 countries, including the United States, Europe, Japan, Korea, Russia, China, Canada, Mexico, and Australia, as well as two regions of China: Hong Kong and Macao. Interestingly, the company hasn't been structured to follow the typical biotech standard when it comes to time and cost. The company already has two revenue-generating subsidiaries, 4P Therapeutics and Pocono Pharmaceutical, along with Active Intelligence, which specializes in sports recovery products. Nutriband’s revenues keep its development burn at a minimum. The company also owns its manufacturing and clinical development capabilities, which significantly reduces its costs for AVERSA and other technologies. Most notably, Nutriband partnered with Kindeva Drug Delivery to develop AVERSA Fentanyl, which combines Nutriband’s AVERSA abuse-deterrent technology with Kindeva’s FDA-approved fentanyl patch. Kindeva Drug Delivery is a leading global contract development and manufacturing organization (CDMO) that has a rich history in pharmaceutical innovation and manufactures millions of transdermal patches distributed worldwide. This strong partnership for AVERSA Fentanyl’s commercial development has led to significant progress in the abuse-deterrent patch’s development and manufacturing. Recently the two companies revised their agreement to formalize their exclusive product development partnership and long-term commitment based on shared development costs in exchange for milestone payments. At the same time, Nutriband revealed that it had signed an Associate Partnership agreement with Charlotte FC, which would be instrumental in helping build visibility for its brands, such as AI Tape. Management noted, “We are very excited to partner with an organization such as Charlotte FC as an Associate Partner. Manufacturing many of our products locally in the Charlotte region through our Pocono subsidiary makes this relationship special.’’ AVERSA’s addressable market is huge, depending on how you look at it. For instance, accidental fentanyl misuse is a growing problem, as illustrated by a recent report that revealed there had been 32 cases of accidental fentanyl exposure, which occurred, resulting in 12 deaths and dozens of hospitalizations, mostly involving young children. This is where the technology comes into play, as it significantly reduces the likelihood of accidental exposure to fentanyl for children. Furthermore, AVERSA Fentanyl is well aligned with the FDA’s Opioids Action Plan mission to expand access to abuse-deterrent formulations (ADFs) and to reduce the risks of misuse not just by the patient but also by other persons who obtain opioids. Upon approval of AVERSA fentanyl, the company expects that the FDA will consider requiring all fentanyl patches to be abuse deterrent, as was required for all oxycontin generics, which could potentially translate to more market share. To put the opportunity here into better context, consider this. According to Health Advances’ assessment, once approved by the FDA, AVERSA Fentanyl is expected to reach peak annual sales of about $200 million. The company believes that conservative pricing will be a key component of capturing and maintaining market share in addition to real-world data and marketing. According to the Health Advances’ report on AVERSA Fentanyl, Nutriband can expect to comfortably charge a 20% premium versus generics while maintaining insurance coverage and support, ideally capturing the market as the safest fentanyl patch in its class. Disclaimers: RazorPitch Inc. "RazorPitch" is not operated by a licensed broker, a dealer, or a registered investment adviser. This content is for informational purposes only and is not intended to be investment advice. The Private Securities Litigation Reform Act of 1995 provides investors a safe harbor in regard to forward-looking statements. Any statements that express or involve discussions with respect to predictions, expectations, beliefs, plans, projections, objectives, goals, assumptions, or future events or performances are not statements of historical fact and may be forward-looking statements. 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April 30, 2025 07:00 AM Eastern Daylight Time

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